Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 6/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636416 | 0.78 | F2 (0.43) | KLK7ROCK2UCHL1AVPR2EPHX2 | |
| Cyclohexylamine SCHEMBL8634493 | 0.77 | F2 (0.44) | PREP | |
| SCHEMBL9543472 | 0.72 | PTPN1 (0.52) | KLK7UCHL1EPHX2KLK5OPRD1 | |
| SCHEMBL9543464 | 0.72 | PTPN1 (0.52) | KLK7UCHL1EPHX2KLK5OPRD1 | |
| SCHEMBL9543253 | 0.72 | PTPN1 (0.52) | KLK7UCHL1EPHX2KLK5OPRD1 | |
| SCHEMBL7429992 | 0.72 | ALDH1A1 (0.69) | KLK7UCHL1EPHX2MEN1KMT2A | |
| SCHEMBL10522061 | 0.70 | PREP (0.64) | KLK7PREPKLK5FKBP1A | |
| SCHEMBL27410636 | 0.70 | HSD17B10 (0.52) | KLK7ROCK2UCHL1PREPKLK5 | |
| SCHEMBL7303538 | 0.69 | F2 (0.49) | PREP | |
| SCHEMBL7303542 | 0.69 | F2 (0.49) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760235-A | DIPEPTIDES BASED ON PROLINE OR PIPECOLIC ACID AND ARGININE ALDEHYDE | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1998-06-02 | — | — | US | disclosed |
| EP-0629212-B1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF | GYOGYSZERKUTATO INTEZET (HU) | 1997-10-08 | — | — | EP | disclosed |
| EP-0629212-A1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. | GYOGYSZERKUTATO INTEZET (HU) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993018060-A1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF | Gyógyszerkutató Intézet Kft. (HU) | 1993-09-16 | — | — | WO | disclosed |