Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.43 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838737 | 0.88 | SLC9A1 (0.47) | SLC9A1PROKR1CYP24A1CYP27A1EPHX2 | |
| SCHEMBL16838798 | 0.85 | PROKR1 (0.50) | SLC9A1PROKR1EPHX2RBP4NOTUM | |
| SCHEMBL22084370 | 0.85 | PROKR1 (0.50) | SLC9A1PROKR1EPHX2RBP4NOTUM | |
| SCHEMBL20010674 | 0.81 | CPS1 (0.40) | GAA | |
| Hydrochloric Acid SCHEMBL4886122 | 0.80 | HTR2C (0.57) | SLC9A1EPHX2HTR2AHTR2CHTR2B | |
| SCHEMBL20010694 | 0.78 | TAS1R3 (0.43) | — | |
| SCHEMBL6437932 | 0.78 | ESR2 (0.45) | CYP24A1CYP26A1LMNAGAAHTR2A | |
| SCHEMBL8990263 | 0.76 | S1PR1 (0.42) | NOTUM | |
| SCHEMBL16838794 | 0.75 | GRM7 (0.47) | SLC9A1CYP24A1CYP27A1GRM7CYP26A1 | |
| SCHEMBL16455076 | 0.74 | HTR2A (0.63) | PROKR1HTR2AHTR2CHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |