SCHEMBL8633780

SCHEMBL8633780

Cc1ccc(C(=CC=Cc2ccc(N(c3ccc(C)cc3)c3ccc(C=CC=C(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
APP P05067 2/20 0.39
MAOB P27338 4/20 0.38
MAOA P21397 3/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
CA1 P00915 1/20 0.38
PTGS2 P35354 2/20 0.37
GAA P10253 4/20 0.36
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPK1 P28482 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALOX5 P09917 1/20 0.36
PTGS1 P23219 1/20 0.36
CYP1B1 Q16678 2/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15275156 1.00 MAPT (0.42) MAPTAPPMAOBMAOAPOLB
SCHEMBL2423809 1.00 MAPT (0.42) MAPTAPPMAOBMAOAPOLB
SCHEMBL2423808 1.00 MAPT (0.42) MAPTAPPMAOBMAOAPOLB
SCHEMBL7750948 1.00 MAPT (0.42) MAPTAPPMAOBMAOAPOLB
SCHEMBL15900022 0.98 MAPT (0.41) MAPTAPPMAOBMAOAPOLB
SCHEMBL15906344 0.98 MAPT (0.41) MAPTAPPMAOBMAOAPOLB
SCHEMBL15906332 0.98 MAPT (0.41) MAPTAPPMAOBMAOAPOLB
SCHEMBL7750910 0.94 ALDH1A1 (0.45) MAPTPOLBPTGS2GAAALDH1A1
SCHEMBL8925952 0.94 MAPT (0.48) MAPTAPPMAOBMAOAPOLB
SCHEMBL13144476 0.94 ALDH1A1 (0.45) MAPTPOLBPTGS2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100233602-A1 Electrophotographic Photoconductor RICOH COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-20100233602-A1 Electrophotographic Photoconductor RICOH COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-7629096-B2 Electrophotographic photoreceptor with an undercoat layer containing a polyimide resin and electrophotographic apparatus with the photoreceptor YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-12-08 US disclosed
US-7629096-B2 Electrophotographic photoreceptor with an undercoat layer containing a polyimide resin and electrophotographic apparatus with the photoreceptor YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-12-08 US disclosed
US-20070154826-A1 Electrophotographic photoreceptor and electrophotograph SHINDENGEN ELECTRIC MFG. CO., LTD. (JP) 2007-07-05 US disclosed
US-20070154826-A1 Electrophotographic photoreceptor and electrophotograph SHINDENGEN ELECTRIC MFG. CO., LTD. (JP) 2007-07-05 US disclosed
US-20070148574-A1 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2007-06-28 US disclosed
US-20070148574-A1 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2007-06-28 US disclosed
EP-0650956-B1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives TAKASAGO PERFUMERY CO LTD (JP) 1998-07-15 EP disclosed
US-5573878-A HIGH CHARGING POTENTIALS, HIGH CARRIER MOBILITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-11-12 US disclosed
US-5567560-A Triphenylamine derivative charge-transporting material containing electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-10-22 US disclosed
EP-0650956-A1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives Takasago International Corporation (JP) 1995-05-03 EP disclosed