Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721393 | 1.00 | MAPT (0.48) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL2423809 | 0.94 | MAPT (0.42) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL15275156 | 0.94 | MAPT (0.42) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL7750948 | 0.94 | MAPT (0.42) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL2423808 | 0.94 | MAPT (0.42) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL8633780 | 0.94 | MAPT (0.42) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL15906332 | 0.92 | MAPT (0.41) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL15906344 | 0.92 | MAPT (0.41) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL15900022 | 0.92 | MAPT (0.41) | MAPTPOLBMAOAMAOBRAB9A | |
| SCHEMBL25071580 | 0.91 | RELA (0.48) | MAPTPOLBMAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9031034-A | — | — | None | — | — | JP | disclosed |
| JP-H0931034-A | CONJUGATED DIENE COMPOUND | RICOH CO LTD | 1997-02-04 | — | — | JP | disclosed |