Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628183 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL7777242 | 0.87 | PTGS2 (0.80) | PTGS2ADORA2AADORA1ADORA3PTGS1 | |
| SCHEMBL8629226 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1PTGIRCA12CA1 | |
| SCHEMBL8628794 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8631051 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1CA9 | |
| SCHEMBL8631461 | 0.83 | PTGS2 (0.49) | PTGS2PTGS1PTGIR | |
| SCHEMBL8631613 | 0.81 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL216154 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8631182 | 0.80 | PTGS2 (0.44) | PTGS2ADORA2AADORA1ADORA3PTGIR | |
| SCHEMBL8631026 | 0.80 | CSNK1D (0.53) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |