Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631182 | 0.92 | PTGS2 (0.44) | PTGS2KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8629992 | 0.89 | PKM (0.48) | PTGS2PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8633781 | 0.89 | PTGS2 (0.67) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8631646 | 0.88 | SMN1; SMN2 (0.54) | PTGS2KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7777584 | 0.86 | PTGS2 (0.63) | PTGS2PTGS1KMT2ACA12CA1 | |
| SCHEMBL8631051 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1KMT2ALMNAMAPT | |
| SCHEMBL8627595 | 0.85 | F10 (0.48) | PTGS2KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL8631512 | 0.85 | LMNA (0.46) | PTGS2KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8629226 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1KMT2ACA12CA1 | |
| SCHEMBL8631613 | 0.83 | PTGS2 (0.43) | PTGS2PTGS1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |