Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.77 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9941851 | 0.87 | CA9 (1.00) | CA9CHRNA7PTGS2PTGS1EPHX2 | |
| SCHEMBL6343758 | 0.83 | CA9 (1.00) | CA9CHRNA7PTGS2SMN1; SMN2CA1 | |
| SCHEMBL3101600 | 0.82 | CA9 (0.72) | CA9CHRNA7PTGS2SMN1; SMN2CA1 | |
| SCHEMBL3100173 | 0.81 | CHRNA7 (1.00) | CA9CHRNA7PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL6342008 | 0.81 | CHRNA7 (1.00) | CA9CHRNA7PTGS2SMN1; SMN2 | |
| SCHEMBL14357207 | 0.81 | CA9 (0.71) | CA9CHRNA7PTGS2SMN1; SMN2CA1 | |
| SCHEMBL3105374 | 0.81 | CA9 (0.80) | CA9CHRNA7PTGS2PTGS1EPHX2 | |
| SCHEMBL13099838 | 0.80 | CA9 (0.69) | CA9CHRNA7PTGS2SMN1; SMN2CA1 | |
| SCHEMBL29352292 | 0.80 | PTGS2 (0.74) | CA9PTGS2PTGS1CA1CA2 | |
| SCHEMBL2917636 | 0.78 | CA9 (0.48) | CA9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830133-A1 | THERAPEUTIC COMPOSITION FOR ARTHRITIS | Takeda Chemical Industries, Ltd. (JP) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996033717-A1 | THERAPEUTIC COMPOSITION FOR ARTHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |