SCHEMBL8633846

SCHEMBL8633846

O=CC(O)C(=O)c1cccc(C(=O)C(O)C=O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.42
CES1 P23141 3/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
UNG P13051 1/20 0.39
GSK3B P49841 1/20 0.38
SLC6A2 P23975 2/20 0.38
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
ITGA5 P08648 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
SLC6A4 P31645 1/20 0.38
CHRNA3 P32297 1/20 0.38
CYP2C19 P33261 1/20 0.38
HRH1 P35367 1/20 0.38
CHRNA7 P36544 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1088403 0.84 CES2 (0.54) CES2CES1TDP1L3MBTL1ATM
SCHEMBL9398543 0.71 ALDH1A1 (0.44) CES2CES1ACHETDP1L3MBTL1
SCHEMBL7945435 0.70 GAA (0.59) ACHETDP1L3MBTL1ATMGSK3B
SCHEMBL27508742 0.68 ALDH1A1 (0.44) CES2CES1TDP1L3MBTL1CYP2C19
SCHEMBL30803096 0.68 CES1 (0.56) CES2CES1TDP1L3MBTL1ATM
SCHEMBL503007 0.67 TDP1 (0.68) CES2CES1TDP1L3MBTL1ATM
SCHEMBL8875628 0.67 CA12 (0.50) TDP1L3MBTL1ATMUNGALDH1A1
SCHEMBL25031716 0.65 TDP1 (0.39) CES2CES1ACHETDP1L3MBTL1
SCHEMBL25029741 0.65 UNG (0.44) CES2CES1ACHETDP1UNG
Isophthalic Acid SCHEMBL11135251 0.65 UNG (0.65) TDP1L3MBTL1ATMUNGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10175949-A None JP disclosed
JP-H10175949-A EXTRACTION OF HYDROPEROXIDE SUMITOMO CHEM CO LTD 1998-06-30 JP disclosed