SCHEMBL8633890

SCHEMBL8633890

CCC(C)CC(F)(F)C(=O)CP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3012774 1.00 LAP3 (0.32) LAP3MMP1MMP2MMP3MEN1
SCHEMBL8412621 0.84 ANPEP (0.37) LAP3MEN1LMNAHPGDTSHR
SCHEMBL8414243 0.84 ANPEP (0.37) LAP3MEN1LMNAHPGDTSHR
SCHEMBL8411160 0.84 LAP3 (0.33) LAP3MEN1LMNAHPGDTSHR
SCHEMBL8412619 0.81
SCHEMBL8414236 0.81
SCHEMBL8413370 0.80 MEN1 (0.32) LAP3MEN1LMNAHPGDTSHR
SCHEMBL8410804 0.74 MEN1 (0.30) MEN1LMNAHPGDTSHRBLM
SCHEMBL8822878 0.73 FDPS (0.40) MEN1LMNAHPGDTSHRBLM
SCHEMBL8630560 0.73 GRIN2D (0.33) LAP3MEN1LMNAHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739161-A PROSTAGLANDINS; DIARRHEA SIDE EFFECT REDUCTION R-TECH UENO, LTD. (JP) 1998-04-14 US disclosed