Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629470 | 0.93 | AVPR2 (0.50) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8634457 | 0.90 | TP53 (0.34) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8634051 | 0.85 | AVPR2 (0.42) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8627671 | 0.84 | AVPR2 (0.37) | AVPR2TP53MAPTGAASMN1; SMN2 | |
| SCHEMBL8629473 | 0.78 | AVPR2 (0.51) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8627187 | 0.76 | AVPR2 (0.40) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8630766 | 0.76 | AVPR2 (0.41) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8627190 | 0.75 | AVPR2 (0.42) | AVPR2SCN5ASCN9ATP53MAPT | |
| SCHEMBL8630392 | 0.75 | ALDH1A1 (0.34) | TP53MAPTGAASMN1; SMN2 | |
| SCHEMBL8634460 | 0.75 | MAPT (0.36) | SCN5ASCN9ATP53MAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |