Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | MLYCD | O95822 | 7/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344045 | 1.00 | IL6ST (0.48) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211410 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL6450744 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211407 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211409 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL7280258 | 0.84 | IL6ST (0.43) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL7280265 | 0.84 | IL6ST (0.43) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL7280251 | 0.84 | IL6ST (0.43) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL6159290 | 0.83 | IL6ST (0.52) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL7428550 | 0.83 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |