SCHEMBL8634141

SCHEMBL8634141

CC(C(F)(F)F)C(F)(F)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8354390 0.79 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL25028393 0.76 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL77807 0.76 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL799182 0.76 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL9472897 0.76 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL8635166 0.73
SCHEMBL11220622 0.73
SCHEMBL12298430 0.72
SCHEMBL19133139 0.71
SCHEMBL22938874 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705716-A COMPOUNDS FOR SOLVENTS AND BLOWING AGENTS ALLIEDSIGNAL INC. (US) 1998-01-06 US disclosed
US-5316690-A Blowing agents or solvents ALLIED SIGNAL INC. (US) 1994-05-31 US disclosed
US-5264044-A Method of cleaning using hydrochlorofluorocarbons having a tertiary structure ALLIEDSIGNAL INC. (US) 1993-11-23 US disclosed
WO-1993006070-A1 HYDROCHLOROFLUOROCARBONS HAVING A TERTIARY STRUCTURE AND OH RATE CONSTANTS WHICH DO NOT CONTRIBUTE SUBSTANTIALLY TO OZONE DEPLETION AND GLOBAL WARMING ALLIED-SIGNAL INC. (US) 1993-04-01 WO disclosed
WO-1993004025-A1 HYDROCHLOROFLUOROCARBONS HAVING OH RATE CONSTANTS WHICH DO NOT CONTRIBUTE SUBSTANTIALLY TO OZONE DEPLETION AND GLOBAL WARMING ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
US-5158617-A Method of cleaning using hydrochlorofluorocarbons having 3 to 5 carbon atoms ALLIED-SIGNAL INC. 1992-10-27 US disclosed
WO-1992016674-A2 A METHOD OF CLEANING USING HYDROCHLOROFLUOROCARBONS HAVING 3 TO 5 CARBON ATOMS ALLIED-SIGNAL INC. (US) 1992-10-01 WO disclosed
US-5146015-A Hydrochlorofluorocarbons having a tertiary structure and OH rate constants which do not contribute substantially to ozone depletion and global warming ALLIED-SIGNAL INC. (US) 1992-09-08 US disclosed