Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847472 | 0.82 | DAO (0.48) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2789975 | 0.81 | MAPT (0.48) | MIFALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL28263654 | 0.81 | SMN1; SMN2 (0.50) | MIFALDH1A1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8634171 | 0.81 | DAO (0.47) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14269795 | 0.77 | MIF (0.40) | MIFALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL18430372 | 0.77 | MIF (0.40) | MIFALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL6694136 | 0.77 | ALDH1A1 (0.56) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11213610 | 0.77 | KMT2A (0.49) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18430395 | 0.77 | HDAC6 (0.49) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1844829 | 0.77 | MIF (0.43) | MIFALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-0719263-B1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES WITH ANTIARRHYTHMIC ACTIVITY | SMITHKLINE BEECHAM LAB (FR) | 1998-07-15 | — | — | EP | disclosed |
| WO-1996027595-A1 | HETEROCYCLYCARBOXAMIDES AND OTHER COMPOUNDS FOR THE TREATMENT OF THE CARDIAC ARRHYTHMIAS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-09-12 | — | — | WO | disclosed |
| EP-0719263-A1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES WITH ANTIARRHYTHMIC ACTIVITY | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007903-A1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES WITH ANTIARRHYTHMIC ACTIVITY | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1995-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | MIF 4865/4885ALDH1A1 271/4885TSHR 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.