Sugi Predict

Sugi Predict / Compounds / SCHEMBL8634235

SCHEMBL8634235

SCHEMBL8634235

Clc1ccc(C2(CC3CCCCC3)CCC2)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC6A3 Q01959 20/20 0.61
▸ SLC6A4 P31645 18/20 0.61
▸ SLC6A2 P23975 12/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997201 0.76 SLC6A4 (0.74) SLC6A3SLC6A4SLC6A2
SCHEMBL3518627 0.76 SLC6A3 (1.00) SLC6A3SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL1375 0.76 SLC6A4 (0.66) SLC6A3SLC6A4SLC6A2
SCHEMBL16691398 0.75 SLC6A4 (0.70) SLC6A3SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL10840117 0.75 SLC6A3 (0.96) SLC6A3SLC6A4SLC6A2
SCHEMBL3519378 0.75 SLC6A3 (1.00) SLC6A3SLC6A4SLC6A2
SCHEMBL8242202 0.75 SLC6A3 (1.00) SLC6A3SLC6A4SLC6A2
SCHEMBL8243516 0.74 SLC6A4 (1.00) SLC6A3SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL3517560 0.73 SLC6A3 (0.97) SLC6A3SLC6A4SLC6A2
SCHEMBL16521001 0.73 SLC6A4 (0.94) SLC6A3SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828484-A1 USE OF ARYL SUBSTITUTED CYCLOBUTYL ALKYL AMINES FOR THE TREATMENT OF OBESITY Knoll AG (DE) 1998-03-18 — — EP disclosed
WO-1996038134-A1 USE OF ARYL SUBSTITUTED CYCLOBUTYL ALKYL AMINES FOR THE TREATMENT OF OBESITY KNOLL AG (DE) 1996-12-05 — — WO disclosed