SCHEMBL8634322

SCHEMBL8634322

C=C(C(=O)O)C(=O)c1ccccc1OO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.44
KDM4E B2RXH2 8/20 0.38
ALDH1A1 P00352 8/20 0.38
HPGD P15428 6/20 0.38
HSD17B10 Q99714 6/20 0.38
ESR1 P03372 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
TSHR P16473 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
BLM P54132 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 2/20 0.37
USP2 O75604 1/20 0.37
PDE3A Q14432 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840677 0.80 HCRTR1 (0.54) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL6832601 0.77 CES2 (0.56) CTNNB1HSD17B10TSHRBLMTDP1
Benzene SCHEMBL28872706 0.76 KDM4E (0.61) CTNNB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL941792 0.76 KDM4E (0.61) CTNNB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL28730239 0.74 KDM4E (0.59) CTNNB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL8104638 0.73 ERCC5 (0.50) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8115300 0.72 ERCC5 (0.49) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8118796 0.72 ERCC5 (0.49) KDM4EALDH1A1HPGDHSD17B10TSHR
Rubidium SCHEMBL8119226 0.72 ERCC5 (0.49) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL7751522 0.71 CTNNB1 (0.70) CTNNB1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714287-A Simulated photographic-quality prints using a transparent substrate containing a wrong reading image and a backing sheet containing an adhesive coating which enhances image optical density XEROX CORPORATION (US) 1998-02-03 US disclosed