SCHEMBL6832601

SCHEMBL6832601

O=C(C(=O)c1ccccc1OO)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 11/20 0.56
CES1 P23141 10/20 0.56
CTNNB1 P35222 1/20 0.47
SLC6A3 Q01959 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
PARP1 P09874 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ELANE P08246 1/20 0.41
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197049 0.86 CES2 (0.58) CES2CES1CTNNB1SLC6A3NPC1
SCHEMBL11508105 0.85 CTNNB1 (0.62) CES2CES1CTNNB1RAB9AMAPT
SCHEMBL5704292 0.82 RAB9A (0.62) CES2CES1SLC6A3NPC1RAB9A
SCHEMBL2857273 0.82 ELANE (0.59) CTNNB1RAB9AMAPTCYP3A4TSHR
SCHEMBL4579639 0.81 HTT (0.61) CES2CES1CTNNB1MAPTTSHR
SCHEMBL6863551 0.81 CES2 (0.52) CES2CES1SLC6A3NPC1RAB9A
SCHEMBL5666795 0.81 CES2 (0.52) CES2CES1SLC6A3NPC1RAB9A
SCHEMBL8574337 0.80 CES2 (0.78) CES2CES1RAB9AMAPTTSHR
SCHEMBL7120215 0.79 CES2 (0.50) CES2CES1SLC6A3NPC1RAB9A
SCHEMBL6369621 0.79 CES2 (0.50) CES2CES1SLC6A3NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040018458-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2004-01-29 US disclosed