Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634360 | 0.91 | FEN1 (0.54) | FEN1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2070130 | 0.88 | MEN1 (0.58) | FEN1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17844004 | 0.84 | NLRP3 (0.55) | FEN1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8658751 | 0.80 | ERCC5 (0.63) | FEN1SMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL30335736 | 0.79 | ERCC5 (0.61) | FEN1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL853580 | 0.79 | ERCC5 (0.61) | FEN1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28166467 | 0.78 | FEN1 (0.71) | FEN1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL10661343 | 0.77 | CES2 (0.48) | SMN1; SMN2KMT2AMEN1POLBNLRP3 | |
| SCHEMBL19849257 | 0.77 | CA12 (0.57) | ALDH1A1SMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL8280364 | 0.77 | GLA (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |