Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627538 | 0.96 | KCNMA1 (0.36) | KMT2AMAPTMEN1KCNMA1POLB | |
| SCHEMBL8627677 | 0.92 | AVPR2 (0.38) | KMT2AMAPTMEN1POLBTP53 | |
| SCHEMBL8634053 | 0.89 | AVPR2 (0.41) | KMT2AMAPTPOLBTP53 | |
| SCHEMBL8629507 | 0.88 | KCNMA1 (0.36) | KMT2AMAPTMEN1KCNMA1POLB | |
| SCHEMBL8627401 | 0.88 | AVPR2 (0.39) | KMT2AMAPTMEN1TP53ALDH1A1 | |
| SCHEMBL8634460 | 0.87 | MAPT (0.36) | KMT2AMAPTMEN1KCNMA1POLB | |
| SCHEMBL8627536 | 0.85 | KCNMA1 (0.35) | KMT2AMAPTMEN1KCNMA1POLB | |
| SCHEMBL8627190 | 0.85 | AVPR2 (0.42) | KMT2AMAPTPOLBTP53 | |
| SCHEMBL8630395 | 0.84 | PDK1 (0.35) | KMT2AMAPTMEN1TP53ALDH1A1 | |
| SCHEMBL8629474 | 0.83 | AVPR2 (0.51) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |