Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442538 | 0.87 | TSHR (0.48) | F10POLBTSHRTDP1DRD2 | |
| SCHEMBL4442532 | 0.87 | TSHR (0.48) | F10POLBTSHRTDP1DRD2 | |
| SCHEMBL7123836 | 0.79 | SIGMAR1 (0.51) | CYP2C19L3MBTL1DRD2HTR2AHTR2C | |
| SCHEMBL15506230 | 0.77 | BLM (0.42) | BLMRECQLF2F10F12 | |
| SCHEMBL11351433 | 0.77 | BLM (0.42) | BLMRECQLF2F10F12 | |
| SCHEMBL27476919 | 0.76 | NPSR1 (0.41) | BLMRECQLF2F10F12 | |
| SCHEMBL7118046 | 0.76 | NPSR1 (0.41) | BLMRECQLF2F10F12 | |
| SCHEMBL27629580 | 0.76 | BLM (0.41) | BLMRECQLF2F10F12 | |
| SCHEMBL23644539 | 0.74 | MAOB (0.46) | BLMRECQLF2F10F12 | |
| SCHEMBL7492443 | 0.74 | MTNR1A (0.43) | HSD17B10L3MBTL1DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750409-A | MARKERS FOR HAPTEN-ANTIBODY-PROTEIN CONJUGATES | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-12 | — | — | US | disclosed |
| EP-0567622-B1 | NEW PENTACYCLIC COMPOUNDS AND THEIR USE AS ABSORPTION OR FLUORESCENCE DYES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1993010189-A1 | NEW PENTACYCLIC COMPOUNDS AND THEIR USE AS ABSORPTION OR FLUORESCENCE DYES | BOEHRINGER MANNHEIM GMBH (DE) | 1993-05-27 | — | — | WO | disclosed |
| EP-0543333-A1 | New pentacyclic compounds and their use as absorption or fluorescence dyestuffs | Roche Diagnostics GmbH (DE) | 1993-05-26 | — | — | EP | disclosed |