Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135010 | 0.88 | BCHE (0.51) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL9143719 | 0.87 | BCHE (0.50) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL9216093 | 0.87 | BCHE (0.50) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL7502637 | 0.84 | BCHE (0.50) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL7502635 | 0.84 | BCHE (0.50) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL4505343 | 0.82 | KMT2A (0.51) | BCHEACHEACEKMT2AL3MBTL1 | |
| SCHEMBL7387452 | 0.79 | GPR119 (0.47) | BCHEACHEGPR119BACE1 | |
| SCHEMBL5566771 | 0.79 | BCHE (0.45) | BCHEACHEKMT2AL3MBTL1GPR119 | |
| SCHEMBL2241423 | 0.78 | KMT2A (0.63) | BCHEACHEKMT2AL3MBTL1BACE1 | |
| SCHEMBL2241424 | 0.78 | KMT2A (0.63) | BCHEACHEKMT2AL3MBTL1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |