Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505343 | 0.94 | KMT2A (0.51) | BCHEACHEGPR119KMT2AL3MBTL1 | |
| SCHEMBL9216093 | 0.88 | BCHE (0.50) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL8634682 | 0.88 | BCHE (0.50) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL9143719 | 0.88 | BCHE (0.50) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL7502635 | 0.85 | BCHE (0.50) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL7502637 | 0.85 | BCHE (0.50) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL7387452 | 0.82 | GPR119 (0.47) | BCHEACHEGPR119BACE1CYP2D6 | |
| SCHEMBL5566771 | 0.81 | BCHE (0.45) | BCHEACHEGPR119KMT2ABACE1 | |
| SCHEMBL9384147 | 0.81 | HRH2 (0.61) | KMT2ABACE1L3MBTL1MEN1 | |
| SCHEMBL7568066 | 0.81 | HRH2 (0.61) | KMT2ABACE1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222395-A1 | New peptide derivatives | ASTRAZENECA AB (SE) | 2005-10-06 | — | — | US | disclosed |
| US-5476950-A | Aminopyrrolidine compound | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5416222-A | Chemical intermediates to prepare pyridinocarboxylic acid derivatives with high antimicrobial activity and excellent pharmacokinetics | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5380874-A | Pyrrolidine carbamates | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5281612-A | Naphthyridine antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5098912-A | Bactericides for grampositive bacteria | DAIICHI SEIYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0207420-A2 | Pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222395-A1 | New peptide derivatives | SERPINE1, SERPINC1, SPINT2 | BCHE 930/4885ACHE 1561/4885GPR119 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.