SCHEMBL86348

SCHEMBL86348

COC(=O)[C@@H](C)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765886 1.00
SCHEMBL295130 1.00
Hydrochloric Acid SCHEMBL722401 0.97
SCHEMBL7105090 0.80 SMN1; SMN2 (0.46)
SCHEMBL1557617 0.80 SMN1; SMN2 (0.46)
SCHEMBL24072865 0.80 SMN1; SMN2 (0.46)
SCHEMBL28353496 0.80 TSHR (0.37)
SCHEMBL12447225 0.79
SCHEMBL6744299 0.79
Methyl 2-Methylbutanoate SCHEMBL1195352 0.79 TDP1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102351901-A 25-hydroxy vitamin D2 series medicament side chain and its preparation method SHANGHAI HAOYUAN CHEMEXPRESS CO LTD 2012-02-15 CN claimed
JP-1261341-A None JP disclosed
JP-7112966-A None JP disclosed
JP-8165263-A None JP disclosed
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors KEZAR LIFE SCIENCES, INC. (US) 2026-04-14 US disclosed
US-12577217-B2 15-PGDH inhibitor KYORIN PHARMACEUTICAL CO., LTD. (JP) 2026-03-17 US disclosed
US-12545684-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2026-02-10 US disclosed
US-20260034106-A1 Macrocyclic ligands for FK506-binding proteins for treatment of diseases with improved characteristics UNIV DARMSTADT TECH (DE) 2026-02-05 US disclosed
EP-4686495-A1 MACROCYCLIC LIGANDS FOR FK506-BINDING PROTEINS FOR TREATMENT OF DISEASES WITH IMPROVED CHARACTERISTICS Technische Universität Darmstadt (DE) 2026-02-04 EP disclosed
EP-4646416-A1 CDK2 INHIBITORS Blueprint Medicines Corporation (US) 2025-11-12 EP disclosed
EP-0480708-A2 Hydroxyalkylquinoline ether acids as leukotriene antagonists MERCK FROSST CANADA INC. (CA) 1992-04-15 EP disclosed
US-5081152-A AZULENE DERIVATIVES AS THROMBOXANE A2 AND PROSTAGLANDIN ENDOPEROXIDE RECEPTOR ANTAGONIST KOTOBUKI SEIYAKU CO., LTD. (JP) 1992-01-14 US disclosed
EP-0251408-B1 NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION THE PROCTER & GAMBLE COMPANY (US) 1991-04-17 EP disclosed
EP-0398474-A2 Oxazole derivatives and intermediates for their preparation MERCK & CO. INC. (US) 1990-11-22 EP disclosed
EP-0389244-A1 Process for synthesis of FK-506 C10-C18 intermediates MERCK & CO. INC. (US) 1990-09-26 EP disclosed
US-4946999-A Novel intermediates for synthesis of trichostatic acid or trichostatin A, and processes for preparing trichostatic acid and trichostatin A JAPAN TOBACCO INC. (JP) 1990-08-07 US disclosed
JP-H01261341-A PREPARATION OF OPTICALLY ACTIVE ALCOHOL NISSHIN FLOUR MILLING CO LTD 1989-10-18 JP disclosed
EP-0331524-A2 Synthesis of trichostatins Japan Tobacco Inc. (JP) 1989-09-06 EP disclosed
EP-0251408-A1 Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation THE PROCTER & GAMBLE COMPANY (US) 1988-01-07 EP disclosed
US-4708966-A SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1987-11-24 US disclosed