SCHEMBL8634811

SCHEMBL8634811

Cc1cc(C)c(OP(Oc2c(C)cc(C)cc2C(C)(C)C)c2ccccc2)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CA2 P00918 1/20 0.36
POLB P06746 1/20 0.36
TYR P14679 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FFAR4 Q5NUL3 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TNFRSF1A P19438 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HSPA5 P11021 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11300513 0.92 ALDH1A1 (0.39) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL14264168 0.89 ALDH1A1 (0.35) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8630837 0.88 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL8658647 0.87 SMN1; SMN2 (0.36) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL13955911 0.87 PPARG (0.35) SMN1; SMN2CYP2D6HSPA5
SCHEMBL11494221 0.86 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL13199354 0.84 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TSHRTDP1
SCHEMBL3418221 0.84 CYP1A2 (0.38) FFAR4TSHRTDP1CYP3A4SLC6A2
SCHEMBL8634091 0.83 ALDH1A1 (0.35) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL10309813 0.82 TDP1 (0.33) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5712403-A CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-27 US disclosed
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed