SCHEMBL8634091

SCHEMBL8634091

Cc1cc(C)c(OP(Oc2c(C)cc(C)cc2C(C)(C)C)c2ccccc2C)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
CA2 P00918 1/20 0.35
POLB P06746 1/20 0.35
TYR P14679 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
HSPA5 P11021 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634811 0.83 ALDH1A1 (0.36) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL14264168 0.78 ALDH1A1 (0.35) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL5196643 0.78 SMN1; SMN2 (0.43) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11056754 0.76 SMN1; SMN2 (0.42) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8658647 0.76 SMN1; SMN2 (0.36) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11494221 0.76 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11270167 0.75 SMN1; SMN2 (0.45) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8630837 0.75 SLC6A2 (0.31)
SCHEMBL13955911 0.74 PPARG (0.35) SMN1; SMN2CYP2D6HSPA5
SCHEMBL11300513 0.73 ALDH1A1 (0.39) ALDH1A1CA2POLBTYRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5712403-A CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-27 US disclosed
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed