Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631725 | 0.91 | AVPR2 (0.40) | CHRM5CHRM1CHRM3WDR5AVPR1A | |
| SCHEMBL8630913 | 0.87 | AVPR1A (0.37) | CHRM5CHRM1CHRM3AVPR1AAVPR2 | |
| SCHEMBL8633400 | 0.83 | AVPR2 (0.40) | CHRM5CHRM1CHRM3WDR5AVPR1A | |
| SCHEMBL8628429 | 0.82 | LMNA (0.43) | CHRM5CHRM1CHRM3AVPR1AAVPR2 | |
| SCHEMBL8634104 | 0.80 | AVPR2 (0.41) | CHRM5CHRM1CHRM3WDR5AVPR1A | |
| Hydrochloric Acid SCHEMBL8631933 | 0.77 | AVPR2 (0.47) | CHRM1AVPR1AAVPR2LMNATP53 | |
| Hydrochloric Acid SCHEMBL8634039 | 0.76 | LMNA (0.45) | CHRM5CHRM1CHRM3AVPR1AAVPR2 | |
| Hydrochloric Acid SCHEMBL8661682 | 0.75 | LMNA (0.44) | CHRM5CHRM1CHRM3AVPR1AAVPR2 | |
| Hydrochloric Acid SCHEMBL8630103 | 0.74 | AVPR2 (0.45) | CHRM1AVPR1AAVPR2LMNATP53 | |
| SCHEMBL8628617 | 0.74 | AVPR1A (0.40) | WDR5AVPR1AAVPR2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |