SCHEMBL8635261

SCHEMBL8635261

CCCCCC1=CCC(c2ccc(F)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.40
SPHK2 Q9NRA0 7/20 0.36
GCGR P47871 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937881 0.87 TP53 (0.33) SPHK1
SCHEMBL2857163 0.83 HTR1A (0.37) SPHK1GCGR
SCHEMBL7940054 0.82 CYP2C9 (0.40)
SCHEMBL7940055 0.82 CYP2C9 (0.40)
SCHEMBL2857284 0.81 SPHK1 (0.35) SPHK1SPHK2
SCHEMBL11162842 0.79 SPHK1 (0.50) SPHK1SPHK2
SCHEMBL8055258 0.77
SCHEMBL8052173 0.77 SPHK1 (0.47) SPHK1SPHK2
SCHEMBL9648854 0.76 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL2856978 0.76 DRD2 (0.33) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571652-B1 Liquid crystalline substituted dihydrobenzene derivatives CITIZEN WATCH CO LTD (JP) 1998-08-05 EP disclosed
US-5342546-A Liquid crystal compositions L.C.C. CONSULTANTS CO., LTD. (JP) 1994-08-30 US disclosed
EP-0571652-A1 Liquid crystalline substituted dihydrobenzene derivatives L.C.C. CONSULTANTS CO., LTD. (JP) 1993-12-01 EP disclosed