Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674664 | 0.84 | POLB (0.46) | PTGS2CES2CES1ALDH1A1KMT2A | |
| SCHEMBL3082313 | 0.81 | PTGS2 (0.38) | PTGS2CES2CES1ALDH1A1KMT2A | |
| SCHEMBL3082311 | 0.81 | PTGS2 (0.38) | PTGS2CES2CES1ALDH1A1KMT2A | |
| SCHEMBL12604508 | 0.81 | KMT2A (0.44) | CES2CES1ALDH1A1KMT2AMAPT | |
| SCHEMBL673966 | 0.81 | KMT2A (0.44) | CES2CES1ALDH1A1KMT2AMAPT | |
| SCHEMBL25795526 | 0.81 | KMT2A (0.44) | CES2CES1ALDH1A1KMT2AMAPT | |
| SCHEMBL12693602 | 0.77 | PTGS2 (0.46) | PTGS2CES2CES1ALDH1A1ATM | |
| SCHEMBL14196492 | 0.77 | PTGS2 (0.46) | PTGS2CES2CES1ALDH1A1ATM | |
| SCHEMBL7118034 | 0.76 | CYP1A2 (0.53) | PTGS2CES2CES1ALDH1A1MAPT | |
| SCHEMBL13009931 | 0.76 | CYP1A2 (0.53) | PTGS2CES2CES1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5698646-A | ANIONIC POLYMERIZATION OF BUTADIENE-STYRENE COPOLYMER USING LITHIUM COMPOUND AND CHELATE COMPOUND | BRIDGESTONE CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0510410-B1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE FIRESTONE INC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0451604-B1 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE FIRESTONE INC (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5354822-A | Endcapping the addition polymerization with a reaction product of an aldimines, a ketimines, a secondary amines and an organo lithium compound prior quenching | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-10-11 | — | — | US | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5268413-A | Blend of functionalized polymer and organolithium compound | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5227431-A | DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0510410-A1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5109907-A | Tire treads with reduced rolling resistance | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5066729-A | Tire Treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0451604-A2 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |