SCHEMBL673966

SCHEMBL673966

CCN=C(c1ccccc1)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
ALDH1A1 P00352 4/20 0.43
MAPT P10636 1/20 0.43
ATM Q13315 1/20 0.42
HSP90AA1 P07900 1/20 0.38
POLB P06746 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HIF1A Q16665 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HPGD P15428 2/20 0.36
GFER P55789 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
G6PC1 P35575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12604508 1.00 KMT2A (0.44) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL25795526 1.00 KMT2A (0.44) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL663133 0.84 ATM (0.39) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL25727587 0.83 KMT2A (0.39) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL673023 0.82 POLB (0.50) KMT2AALDH1A1MAPTATMPOLB
SCHEMBL8635389 0.81 PTGS2 (0.41) KMT2AALDH1A1MAPTATMCES2
SCHEMBL3078037 0.80 ATM (0.39) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL3078036 0.80 ATM (0.39) KMT2AALDH1A1MAPTATMHSP90AA1
SCHEMBL11684673 0.77 ALDH1A1 (0.45) ALDH1A1POLBHSD17B10HPGD
SCHEMBL15516659 0.76 ALDH1A1 (0.48) KMT2AALDH1A1MAPTATMHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP claimed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP claimed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO claimed
US-11680153-B2 Rubber composition LG CHEM, LTD. 2023-06-20 US disclosed
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
EP-3715388-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME LG CHEMICAL LTD (KR) 2023-04-26 EP disclosed
US-11421053-B2 Conjugated diene-based polymer and method for preparing the same LG CHEM, LTD. 2022-08-23 US disclosed
US-11384178-B2 2022-07-12 US disclosed
US-5310798-A Tire treads BRIDGESTONE/FIRESTONE, INC. (US) 1994-05-10 US disclosed
US-5227431-A DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE BRIDGESTONE/FIRESTONE, INC. (US) 1993-07-13 US disclosed
EP-0510410-A1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE/FIRESTONE, INC. (US) 1992-10-28 EP disclosed
US-5109907-A Tire treads with reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-05 US disclosed
US-5066729-A Tire Treads BRIDGESTONE/FIRESTONE, INC. (US) 1991-11-19 US disclosed
EP-0451604-A2 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-16 EP disclosed