Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635724 | 0.98 | LMNA (0.52) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL8423674 | 0.93 | LMNA (0.56) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL3430438 | 0.92 | LMNA (0.58) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL11299901 | 0.92 | LMNA (0.58) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL8411032 | 0.85 | LMNA (0.49) | LMNAMAP2K1 | |
| SCHEMBL7772911 | 0.85 | LMNA (0.52) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL8413023 | 0.83 | LMNA (0.50) | LMNAMAP2K1 | |
| SCHEMBL9265234 | 0.83 | LMNA (0.50) | LMNAMAP2K1 | |
| SCHEMBL8411034 | 0.82 | LMNA (0.49) | LMNAMAP2K1 | |
| SCHEMBL9269955 | 0.82 | LMNA (0.47) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763663-A | REACTING 5-HYDROXY-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLIC ACID DIAMIDE WITH AMIDE HAVING REACTIVE SUBSTITUENT | DIBRA S.P.A. (IT) | 1998-06-09 | — | — | US | disclosed |
| US-5728877-A | ETHERIFICATION OF IODINATED BENZENEDICARBOXYLIC ACID AMIDES, INTERMEDIATES FOR X-RAY CONTRAST MEDIA | DIBRA S.P.A. (IT) | 1998-03-17 | — | — | US | disclosed |