Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423674 | 0.98 | LMNA (0.56) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL8635724 | 0.93 | LMNA (0.52) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL8635540 | 0.92 | LMNA (0.51) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL8413023 | 0.91 | LMNA (0.50) | LMNAMAP2K1 | |
| SCHEMBL8411032 | 0.90 | LMNA (0.49) | LMNAMAP2K1 | |
| SCHEMBL8411034 | 0.90 | LMNA (0.49) | LMNAMAP2K1 | |
| SCHEMBL8978048 | 0.87 | LMNA (0.48) | LMNACYP2C19HIF1A | |
| SCHEMBL9264427 | 0.86 | LMNA (0.47) | LMNA | |
| SCHEMBL14777479 | 0.86 | LMNA (0.52) | LMNACYP2C19HIF1AMAP2K1TYMP | |
| SCHEMBL9269955 | 0.86 | LMNA (0.47) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254850-B1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2016-06-22 | — | — | EP | disclosed |
| EP-2254850-B1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2016-06-22 | — | — | EP | disclosed |
| US-9193659-B2 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| US-9193659-B2 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| US-9193659-B2 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| EP-2580187-B1 | Process for the iodination of phenolic derivatives | BRACCO IMAGING SPA (IT) | 2015-05-27 | — | — | EP | disclosed |
| US-8835685-B2 | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2014-09-16 | — | — | US | disclosed |
| US-8835685-B2 | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2014-09-16 | — | — | US | disclosed |
| EP-2593423-B1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2014-09-03 | — | — | EP | disclosed |
| EP-2593423-B1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2014-09-03 | — | — | EP | disclosed |
| US-20100331567-A1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2010-12-30 | — | — | US | disclosed |
| US-20100331567-A1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2010-12-30 | — | — | US | disclosed |
| EP-2254850-A2 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | Bracco Imaging S.p.A (IT) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009103666-A2 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103666-A2 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2009-08-27 | — | — | WO | disclosed |
| EP-2093206-A1 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.p.A. (IT) | 2009-08-26 | — | — | EP | disclosed |
| EP-2093206-A1 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.p.A. (IT) | 2009-08-26 | — | — | EP | disclosed |
| EP-0782562-B1 | PROCESS FOR THE MANUFACTURING OF IODINATED CONTRAST AGENTS | BRACCO SPA (IT) | 1999-10-13 | — | — | EP | disclosed |
| EP-0707572-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.p.A. (IT) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001966-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.P.A. (IT) | 1995-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331567-A1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | TPO, NISCH, TYR | LMNA 4341/4885CYP2C19 90/4885HIF1A 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.