⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140746 | 1.00 | — | — | |
| SCHEMBL10100221 | 1.00 | — | — | |
| SCHEMBL25959621 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL18702567 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL10120770 | 0.80 | — | — | |
| SCHEMBL2959559 | 0.80 | — | — | |
| SCHEMBL6933816 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL15895449 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL20707209 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL22628561 | 0.78 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534907-B1 | The use of furanone derivatives for the prevention or treatment of autoimmune diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1998-08-05 | — | — | EP | claimed |
| US-5532271-A | TREATMENT OF RHEUMATOID ARTHRITIS, MULTIPLE SCLEROSIS, ENCEPHALOMYELITIS, HEMOLYTIC ANEMIA | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5376682-A | Autoimmune diseases | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| EP-0534907-A1 | The use of furanone derivatives for the prevention or treatment of autoimmune diseases | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | claimed |
| EP-0534907-B1 | The use of furanone derivatives for the prevention or treatment of autoimmune diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1998-08-05 | — | — | EP | disclosed |
| EP-0534907-A1 | The use of furanone derivatives for the prevention or treatment of autoimmune diseases | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |