Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 6/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | NPC1 | O15118 | 5/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.80 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.80 |
| ▸ | STAT1 | P42224 | 1/20 | 0.80 |
| ▸ | CASP3 | P42574 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.80 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622365 | 0.91 | ALDH2 (1.00) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10622990 | 0.90 | ALDH2 (0.78) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| Ipriflavone SCHEMBL29485035 | 0.89 | ALDH1A1 (1.00) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| Ipriflavone SCHEMBL111472 | 0.89 | ALDH1A1 (1.00) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10802161 | 0.88 | ALDH2 (0.72) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10713380 | 0.88 | ALDH2 (0.82) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28048765 | 0.86 | ALDH1A1 (0.77) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL27486577 | 0.85 | MAPT (0.71) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL11557001 | 0.84 | ALDH1A1 (0.78) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2070406 | 0.82 | NPC1 (1.00) | ALDH2ALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116448933-A | Metabolite marker combination and method for deducing blood trace remaining time in 24 hours | 山西医科大学 | 2023-07-18 | — | — | CN | claimed |
| US-4644012-A | WITH 3-PHENYL-4H-1-BENZOPYRAN-4-ONE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| EP-0146922-A2 | Benzopyran-4-on derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | claimed |
| WO-1998024419-A1 | IPRIFLAVONE COMPOSITION | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1998-06-11 | — | — | WO | disclosed |
| US-4772627-A | AMORPHOUS DRUG AND ADSORBENT, IMPROVED DISSOLUTION AND ADSORPTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-20 | — | — | US | disclosed |
| US-4644012-A | WITH 3-PHENYL-4H-1-BENZOPYRAN-4-ONE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| EP-0146921-A2 | Method for treating osteoporosis | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0146922-A2 | Benzopyran-4-on derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0129893-A2 | Ground mixture | Takeda Chemical Industries, Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |