Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.51 |
| ▸ | TUBB | P07437 | 4/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881152 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL699458 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL699457 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL14950253 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL631998 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL13790336 | 0.74 | RELA (0.81) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5492159 | 0.74 | CYP1A1 (0.66) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5492154 | 0.74 | CYP1A1 (0.66) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL29288695 | 0.72 | RELA (0.77) | RELATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL8636985 | 0.72 | TUBB1 (0.52) | RELATUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516257-B1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AG (DE) | 1998-08-05 | — | — | EP | disclosed |
| WO-1992021669-A1 | 2-PHENYLBENZO[B]FURANS AND THIOPHENES, METHODS OF PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-10 | — | — | WO | disclosed |
| EP-0516257-A1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |