SCHEMBL699457

SCHEMBL699457

COc1ccc(/C=C/c2ccc(OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.81
TRPA1 O75762 1/20 0.81
CYP1A2 P05177 3/20 0.77
CYP1A1 P04798 3/20 0.77
CYP1B1 Q16678 3/20 0.77
TUBB1 Q9H4B7 3/20 0.77
ESR1 P03372 2/20 0.77
PTGS2 P35354 2/20 0.77
TUBB4A P04350 2/20 0.77
TUBB P07437 2/20 0.77
TUBA3C P0DPH7 2/20 0.77
AHR P35869 2/20 0.77
TUBA1B P68363 2/20 0.77
TUBA4A P68366 2/20 0.77
TUBB4B P68371 2/20 0.77
TUBB3 Q13509 2/20 0.77
TUBB2A Q13885 2/20 0.77
TUBB8 Q3ZCM7 2/20 0.77
TUBA3E Q6PEY2 2/20 0.77
TUBA1A Q71U36 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14950253 1.00 RELA (0.81) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL699458 1.00 RELA (0.81) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL4881152 1.00 RELA (0.81) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL631998 1.00 RELA (0.81) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL13790336 1.00 RELA (0.81) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL29288695 0.97 RELA (0.77) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL25233853 0.92 RELA (0.71) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL20032248 0.92 RELA (0.71) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL13267811 0.92 RELA (0.71) RELATRPA1CYP1A2CYP1A1CYP1B1
SCHEMBL9177232 0.92 TUBB1 (0.83) RELATRPA1CYP1A2CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113499327-A Application of trans-4, 4' -dimethoxystilbene compound in preparation of neuroleptic drugs 南通市第一人民医院 2021-10-15 CN claimed
US-20110086429-A1 METHODS AND DEVICES FOR DETECTING OZONE AND CARBONYL-CONTAINING COMPOUNDS SIGMA-ALDRICH CO. (US) 2011-04-14 US claimed
EP-2232254-A1 METHODS AND DEVICES FOR SIMULTANEOUSLY DETECTING OZONE AND CARBONYL- CONTAINING COMPOUNDS Sigma-Aldrich Co. (US) 2010-09-29 EP claimed
WO-2009086304-A1 METHODS AND DEVICES FOR SIMULTANEOUSLY DETECTING OZONE AND CARBONYL- CONTAINING COMPOUNDS SIGMA-ALDRICH CO. (US) 2009-07-09 WO claimed
US-4293717-A Process for preparing aldehydes and diols BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US claimed
EP-0001910-B1 PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF MONSANTO COMPANY (US) 1981-09-02 EP claimed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US claimed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP claimed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 US disclosed
CN-113499327-A Application of trans-4, 4' -dimethoxystilbene compound in preparation of neuroleptic drugs 南通市第一人民医院 2021-10-15 CN disclosed
CN-113499327-A Application of trans-4, 4' -dimethoxystilbene compound in preparation of neuroleptic drugs 南通市第一人民医院 2021-10-15 CN disclosed
CN-113499327-A Application of trans-4, 4' -dimethoxystilbene compound in preparation of neuroleptic drugs 南通市第一人民医院 2021-10-15 CN disclosed
US-20210228501-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2021-07-29 US disclosed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US disclosed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed
US-3972944-A BORON OXIDE, BORIC ACID OR BORATE AND VANADIUM OR MOLYBDENUM CONTAINING CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3952193-A Imaging method with U.V. excitation of liquid crystal XEROX CORPORATION (US) 1976-04-20 US disclosed
US-3936640-A Imaging system XEROX CORPORATION (US) 1976-02-03 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB RELA 625/4885TRPA1 2538/4885CYP1A2 3735/4885
US-20210228501-A1 Formulation and Process for Modulating Wound Healing ATG7, SQSTM1, ATF4 RELA 974/4885TRPA1 1787/4885CYP1A2 3414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.