Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759158 | 0.88 | L3MBTL1 (0.50) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL11548787 | 0.84 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL11101131 | 0.82 | MAPT (0.56) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL4270804 | 0.82 | MAPT (0.61) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL7913579 | 0.81 | HDAC8 (0.55) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL1906865 | 0.81 | L3MBTL1 (0.62) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL30989217 | 0.81 | L3MBTL1 (0.62) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL11727313 | 0.80 | CA12 (0.47) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL8634975 | 0.80 | KDM4E (0.47) | ALDH1A1L3MBTL1NPSR1NPC1RAB9A | |
| Ethyl Propionate SCHEMBL27784379 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1MAPTL3MBTL1NPSR1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601191-B1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KK (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5371225-A | Immunosuppressants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0601191-A1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-3997589-A | ANTIPHLOGISTIC, ANTIPROLIFERATIVES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-12-14 | — | — | US | disclosed |