SCHEMBL8635684

SCHEMBL8635684

ClC(Cl)=CCOc1ccc(Oc2ccc(Cl)cc2)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PPARA Q07869 5/20 0.39
PPARG P37231 3/20 0.39
TSHR P16473 1/20 0.38
FFAR1 O14842 1/20 0.38
PPARD Q03181 3/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633930 0.90 TDP1 (0.38) TDP1PPARAPPARGTSHRPPARD
SCHEMBL8651091 0.90 TDP1 (0.48) TDP1TSHRFFAR1HTTALDH1A1
SCHEMBL8635410 0.90 HSP90AA1 (0.46) PPARAPPARGHTTHTR2ASLC6A4
SCHEMBL8636578 0.89 HTR2A (0.41) TDP1PPARAPPARGPPARDHTT
SCHEMBL8635559 0.89 PPARA (0.50) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL8634454 0.87 PPARD (0.40) TDP1MAOBPPARAPPARGFFAR1
SCHEMBL8632796 0.87 TDP1 (0.41) TDP1MAOAMAOBPPARAPPARG
SCHEMBL8632579 0.86 NPC1 (0.38) MAOAMAOBTSHRHTTALDH1A1
SCHEMBL8638216 0.85 PPARA (0.41) PPARAPPARGFFAR1PPARDHTT
SCHEMBL8635753 0.84 HTT (0.38) MAOAMAOBTSHRHTTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed