SCHEMBL8632796

SCHEMBL8632796

Clc1ccc(Oc2ccc(OCC=C(Br)Br)c(Cl)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
PPARA Q07869 5/20 0.38
PPARG P37231 3/20 0.38
PPARD Q03181 4/20 0.38
TSHR P16473 2/20 0.38
FFAR1 O14842 1/20 0.37
HTR2A P28223 1/20 0.37
SLC6A4 P31645 1/20 0.37
GAA P10253 1/20 0.37
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633165 0.90 TDP1 (0.37) TDP1PPARAPPARGPPARDTSHR
SCHEMBL8632883 0.88 PPARD (0.39) TDP1MAOBPPARAPPARGPPARD
SCHEMBL8633759 0.87 PNLIP (0.38) MAOAMAOBFFAR1HTR2ASLC6A4
SCHEMBL8635684 0.87 TDP1 (0.42) TDP1MAOAMAOBPPARAPPARG
SCHEMBL8632023 0.84 PPARD (0.40) TDP1MAOBPPARAPPARDTSHR
SCHEMBL8638737 0.80 HTR2A (0.43) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL8632925 0.79 FFAR1 (0.50) TDP1PPARAPPARDFFAR1HTR2A
SCHEMBL8636441 0.78 EPAS1 (0.38) TSHRGAAALDH1A1KDM4EMAPT
SCHEMBL8637045 0.77 PKM (0.37) TDP1TSHRALDH1A1L3MBTL1CYP1A2
SCHEMBL8651091 0.77 TDP1 (0.48) TDP1TSHRFFAR1HTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed