Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 11/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638216 | 0.90 | PPARA (0.41) | PPARAPPARGPPARD | |
| SCHEMBL8635684 | 0.89 | TDP1 (0.42) | PPARAPPARGPPARDHTR2ASLC6A4 | |
| SCHEMBL8632019 | 0.88 | FFAR4 (0.47) | PPARAPPARGPPARD | |
| SCHEMBL8635410 | 0.87 | HSP90AA1 (0.46) | PPARAPPARGHTR2ASLC6A4KCNH2 | |
| SCHEMBL8636578 | 0.86 | HTR2A (0.41) | PPARAPPARGPPARDHTR2ASLC6A4 | |
| SCHEMBL8633930 | 0.84 | TDP1 (0.38) | PPARAPPARGPPARDHTR2ASLC6A4 | |
| SCHEMBL8634454 | 0.82 | PPARD (0.40) | PPARAPPARGPPARDHTR2ASLC6A4 | |
| SCHEMBL8651091 | 0.82 | TDP1 (0.48) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL8632081 | 0.80 | PPARD (0.40) | PPARAPPARDHTR2ASLC6A4KCNH2 | |
| SCHEMBL8635697 | 0.80 | ALDH1A1 (0.46) | PPARAPPARDHTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025160-A1 | OXEPANE NUCLEOSIDES AND OLIGONUCLEOTIDES, USES THEREOF AND METHODS OF MAKING THE SAME | MCGILL UNIVERSITY (CA) | 2008-03-06 | — | — | WO | disclosed |
| EP-0648729-B1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5530015-A | Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648729-A1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |