Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049939 | 0.84 | TSHR (0.38) | ALDH1A1LMNACYP3A4MAPTUSP2 | |
| SCHEMBL14095430 | 0.84 | SLC7A5 (0.42) | ALDH1A1CYP3A4TSHRPSMB5 | |
| SCHEMBL26231086 | 0.84 | SLC7A5 (0.42) | ALDH1A1CYP3A4TSHRPSMB5 | |
| SCHEMBL26231092 | 0.84 | SLC7A5 (0.42) | ALDH1A1CYP3A4TSHRPSMB5 | |
| SCHEMBL8119427 | 0.83 | TSHR (0.36) | ALDH1A1CYP3A4MAPTTSHRPSMB5 | |
| SCHEMBL16130378 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNALPAR3LPAR2CYP3A4 | |
| SCHEMBL6368605 | 0.82 | SLC7A5 (0.44) | ALDH1A1CYP3A4TSHRPSMB5 | |
| SCHEMBL8120464 | 0.81 | MAPT (0.35) | ALDH1A1CYP3A4MAPTTSHRPSMB5 | |
| SCHEMBL4202943 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNALPAR3LPAR2CYP3A4 | |
| SCHEMBL27722089 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNALPAR3LPAR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770084-A | SEPARATING THE MIXTURE OF TWO ENANTIOMERS BY USING CHIRAL SELECTOR AND POLYMERIZED CHIRAL MICELLES HAVING DIFFERENT AFFINITIES FOR ENANTIOMERS WHICH CAUSES THE ENANTIOMERS TO MOVE THROUGH MEDIUM AT DIFFERENT VELOCITIES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1998-06-23 | — | — | US | disclosed |