SCHEMBL8635741

SCHEMBL8635741

O=C(NCC1CO1)C(=O)NCC1CO1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
KMT2A Q03164 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 2/20 0.42
SMN1; SMN2 Q16637 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
NPSR1 Q6W5P4 1/20 0.39
USP2 O75604 1/20 0.38
PKM P14618 1/20 0.38
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
MTNR1A P48039 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11421378 0.84 HPGD (0.43) LMNAKMT2AALDH1A1MEN1SMN1; SMN2
SCHEMBL183586 0.83 ALDH1A1 (0.47) LMNAKMT2AALDH1A1MEN1SMN1; SMN2
SCHEMBL3832973 0.82
SCHEMBL16197619 0.82
SCHEMBL3832969 0.82
SCHEMBL10704683 0.81 MTNR1A (0.37) LMNAKMT2AALDH1A1MEN1SMN1; SMN2
SCHEMBL2863034 0.80
SCHEMBL4663635 0.80
SCHEMBL18610948 0.80
SCHEMBL1259779 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111629816-A Asymmetric composite membranes and uses thereof 加州大学评议会 2020-09-04 CN disclosed
EP-0655472-B1 Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENIRICERCHE SPA (IT) 1998-07-29 EP disclosed
EP-0546602-B1 Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM SPA (IT) 1996-07-24 EP disclosed
US-5489664-A Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENICHEM S.P.A. (IT) 1996-02-06 US disclosed
EP-0514994-B1 Liquid compositions based on polyisocyanates and epoxides ENICHEM SPA (IT) 1995-09-06 EP disclosed
EP-0655472-A1 Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENIRICERCHE S.p.A. (IT) 1995-05-31 EP disclosed
US-5326833-A Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.P.A. (IT) 1994-07-05 US disclosed
EP-0598433-A2 Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.p.A. (IT) 1994-05-25 EP disclosed
US-5314983-A Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.P.A. (IT) 1994-05-24 US disclosed
US-5288833-A Thermosetting resin with high softening point ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1994-02-22 US disclosed
EP-0297396-B1 LAMINATE OF SHEET METAL AND DUROPLASTIC; METHOD OF MAKING SUCH A LAMINATE AND ITS USE IN THE MANUFACTURE OF CARS DSM N.V. (NL) 1993-09-08 EP disclosed
EP-0546602-A1 Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.p.A. (IT) 1993-06-16 EP disclosed
US-5194334-A Compression molded plastic/metal composites, unsaturated polyester, epoxy resin DSM N.V. 1993-03-16 US disclosed
EP-0514994-A1 Liquid compositions based on polyisocyanates and epoxides ENICHEM S.p.A. (IT) 1992-11-25 EP disclosed