SCHEMBL8635860

SCHEMBL8635860

[NH]c1nc(Cl)c(Cl)c(Cl)n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218726 0.69 ALDH1A1 (0.54) CYP1A2
SCHEMBL479536 0.67
SCHEMBL468366 0.65 ALDH1A1 (0.36)
SCHEMBL376722 0.64 LMNA (0.39) CYP1A2
SCHEMBL2118610 0.64 CYP1A2 (0.30) CYP1A2
SCHEMBL6401587 0.64 TDP1 (0.32) CYP1A2
SCHEMBL5261298 0.64 TDP1 (0.42) CYP1A2
SCHEMBL6560104 0.62
SCHEMBL1427437 0.62
Ammonia Solution, Strong SCHEMBL9646819 0.62 ALDH1A1 (0.43) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882098-A1 DYES CONTAINING A 2,4,5-TRIFLUORO-3,6-DICYANOPHENYL REACTIVE GROUP AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1998-12-09 EP disclosed
US-5759247-A COLORING PAPER, PLASTICS, TEXTILES ZENECA LIMITED (GB) 1998-06-02 US disclosed
WO-1997027250-A1 DYES CONTAINING A 2,4,5-TRIFLUORO-3,6-DICYANOPHENYL REACTIVE GROUP AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1997-07-31 WO disclosed
US-5451666-A Reactive dyes having a triazine group which is substituted by hydrogen or an alkyl group ZENECA LIMITED (GB) 1995-09-19 US disclosed
US-5373094-A Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine group ZENECA LIMITED (GB) 1994-12-13 US disclosed
US-5359043-A Reactive dyes having a sulphonamido group ZENECA LIMITED (GB) 1994-10-25 US disclosed
EP-0578357-A1 Water soluble reactive dyes ZENECA LIMITED (GB) 1994-01-12 EP disclosed
EP-0576143-A2 Reactive dyes containing a 2,6-difluoro-3,5-dichloropyridine-4-ylamino group ZENECA LIMITED (GB) 1993-12-29 EP disclosed
EP-0359188-B1 Dyeing and printing process of cellulose fibres in the absence of alkali or reducing agents HOECHST AG (DE) 1993-12-15 EP disclosed
EP-0514001-A1 Reactive dyes ZENECA LIMITED (GB) 1992-11-19 EP disclosed
US-4988365-A Eliminates need for alkali or reducing agent for subsequent dyeing HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
EP-0402879-A1 Process to obtain design effects by dying or printing of textile material without alkali or reductor agent HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-19 EP disclosed
EP-0359188-A2 Dyeing and printing process of cellulose fibres in the absence of alkali or reducing agents HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-21 EP disclosed
EP-0358174-A2 Thermofixation process for dyeing and printing with reactive dyes or water soluble sulfur dyes in the absence of alkali or reducing agents HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-14 EP disclosed
US-4806126-A PRETREATING WITH WETTING AGENT AND REACTION PRODUCT OF POLYETHYLENIMINE AND BIFUNCTIONAL ALKLATING AGENT HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-21 US disclosed
EP-0284010-A2 Process for alkali-free dyeing and printing HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-28 EP disclosed
US-4169705-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-02 US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 US disclosed
US-4147510-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-04-03 US disclosed
US-4134723-A DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-16 US disclosed