SCHEMBL8635931

SCHEMBL8635931

CCOc1ccc(Oc2cc(C(C)(C)C)c(OCC=C(Cl)Cl)cc2C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
HTT P42858 1/20 0.36
LTA4H P09960 2/20 0.35
LMNA P02545 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TBXA2R P21731 1/20 0.33
SLC5A2 P31639 1/20 0.33
NQO1 P15559 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633527 0.88 LTA4H (0.35) MAPTLTA4HLMNAATML3MBTL1
SCHEMBL8635990 0.84 LTA4H (0.41) MAPTHTTLTA4HLMNAATM
SCHEMBL8637011 0.80 MAPT (0.44) MAPTHTTLTA4HLMNAATM
SCHEMBL8635048 0.74 MAPT (0.44) MAPTHTTLTA4HLMNAATM
SCHEMBL8634090 0.74 SMN1; SMN2 (0.50) MAPTHTTALDH1A1SMN1; SMN2TSHR
SCHEMBL8638987 0.74 PPARA (0.36) MAPTHTTALDH1A1MEN1KMT2A
SCHEMBL8631816 0.72 LTA4H (0.41) MAPTLTA4HLMNAATML3MBTL1
SCHEMBL8634705 0.72 LTA4H (0.43) MAPTHTTLTA4HLMNAATM
SCHEMBL8632642 0.71 LTA4H (0.42) MAPTHTTLTA4HLMNAATM
SCHEMBL8633420 0.71 MAPT (0.42) MAPTHTTLTA4HLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed