SCHEMBL8638987

SCHEMBL8638987

Cc1cc(OCC=C(Cl)Cl)c(Cl)cc1Oc1ccc(OCC(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 6/20 0.36
HTT P42858 2/20 0.36
PPARD Q03181 5/20 0.35
PPARG P37231 3/20 0.35
ALDH1A1 P00352 1/20 0.34
FFAR1 O14842 3/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CYP2C9 P11712 2/20 0.33
CYP1A2 P05177 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633455 0.90 PPARA (0.36) PPARAHTTPPARDPPARGALDH1A1
SCHEMBL8636315 0.85 PPARD (0.43) PPARAHTTPPARDALDH1A1FFAR1
SCHEMBL8633395 0.82 ALDH1A1 (0.39) PPARAHTTPPARDPPARGALDH1A1
SCHEMBL8633096 0.81 HTT (0.34) HTTFFAR1FFAR4
SCHEMBL8635751 0.80 HTT (0.46) HTTPPARDFFAR1MAPT
SCHEMBL8636074 0.76 KDM4E (0.37) PPARAHTTALDH1A1MEN1MAPT
SCHEMBL8635931 0.74 MAPT (0.36) HTTALDH1A1MEN1MAPTKMT2A
SCHEMBL8634698 0.73 HTT (0.37) HTTFFAR1FFAR4CYP1A2CYP2C19
SCHEMBL8635064 0.72 CYP1A2 (0.47) ALDH1A1FFAR1MAPTKMT2ACYP1A2
SCHEMBL8633632 0.71 FFAR1 (0.51) PPARAPPARDFFAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed