Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773822 | 0.85 | RAB9A (0.61) | RAB9ANPC1ALDH1A1ESR1ESR2 | |
| SCHEMBL13814475 | 0.84 | PHLPP2 (0.56) | PHLPP2LMNATSHRRAB9ANPC1 | |
| SCHEMBL2649812 | 0.83 | PHLPP2 (0.68) | PHLPP2CHRNB2CHRNA4LMNATSHR | |
| SCHEMBL13814417 | 0.83 | PHLPP2 (0.55) | PHLPP2LMNATSHRRAB9AALDH1A1 | |
| SCHEMBL19563523 | 0.83 | PHLPP2 (0.55) | PHLPP2LMNATSHRRAB9AALDH1A1 | |
| SCHEMBL11288528 | 0.83 | GAA (0.56) | PHLPP2LMNATSHRRAB9AALDH1A1 | |
| SCHEMBL161923 | 0.82 | LMNA (0.66) | LMNATSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL65544 | 0.82 | PHLPP2 (0.70) | PHLPP2LMNATSHRRAB9AALDH1A1 | |
| SCHEMBL11020137 | 0.82 | TDP1 (0.63) | LMNATSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL13804068 | 0.81 | PHLPP2 (0.56) | PHLPP2LMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8008243-A | — | — | None | — | — | JP | disclosed |
| JP-8006249-A | — | — | None | — | — | JP | disclosed |
| US-5753407-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5585217-A | Polyamic acid composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-12-17 | — | — | US | disclosed |
| JP-H088243-A | SEMICONDUCTOR DEVICE | TOSHIBA CHEM CORP | 1996-01-12 | — | — | JP | disclosed |
| JP-H086249-A | PHOTOSENSITIVE RESIN COMPOSITION | TOSHIBA CHEM CORP | 1996-01-12 | — | — | JP | disclosed |