Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455674 | 0.89 | CYP4F2 (0.71) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL1151562 | 0.88 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAAKMT2A | |
| SCHEMBL18458202 | 0.86 | CYP4F2 (0.67) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL8567928 | 0.84 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL69660 | 0.82 | CYP4F2 (0.86) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL6282888 | 0.82 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL13921686 | 0.81 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 | |
| SCHEMBL8632267 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1PTPN1KMT2A | |
| SCHEMBL27859213 | 0.79 | CYP4F2 (0.57) | CYP4F2CYP4A11ALDH1A1GAAKMT2A | |
| SCHEMBL28008696 | 0.79 | CYP4F2 (0.81) | CYP4F2CYP4A11ALDH1A1GAAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601191-B1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KK (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0601191-A1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |