Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727313 | 0.86 | CA12 (0.47) | ALDH1A1MAPTSMN1; SMN2CYP4Z1L3MBTL1 | |
| SCHEMBL8184277 | 0.83 | EPHX2 (0.60) | CYP4F2CYP4A11PTPN1TDP1CYP4Z1 | |
| SCHEMBL11759158 | 0.82 | L3MBTL1 (0.50) | CYP4F2CYP4A11ALDH1A1MAPTMEN1 | |
| SCHEMBL2772418 | 0.82 | CYP4F2 (0.68) | CYP4F2CYP4A11PTPN1TDP1CYP4Z1 | |
| SCHEMBL11804328 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHCAR2MEN1CYP3A4 | |
| SCHEMBL3171329 | 0.81 | CYP11B1 (0.49) | CYP4F2CYP4A11ALDH1A1MAPTPTPN1 | |
| SCHEMBL27466269 | 0.81 | GRIA4 (0.46) | ALDH1A1MAPTHCAR2MEN1CYP3A4 | |
| SCHEMBL11453894 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTHCAR2MEN1CYP3A4 | |
| SCHEMBL15539472 | 0.80 | FFAR1 (0.55) | CYP4F2CYP4A11PTPN1FFAR1FFAR4 | |
| SCHEMBL8636007 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601191-B1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KK (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5371225-A | Immunosuppressants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0601191-A1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |