Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 4/20 | 0.49 |
| ▸ | TACR2 | P21452 | 3/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641331 | 0.92 | ALDH1A1 (0.52) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8639998 | 0.92 | TACR2 (0.51) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8636061 | 0.91 | TACR2 (0.49) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8355595 | 0.91 | HRH1 (0.56) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8640838 | 0.90 | HRH1 (0.53) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8353694 | 0.90 | HRH1 (0.55) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL7947406 | 0.89 | PKM (0.52) | HRH1PKMTACR1TACR2TACR3 | |
| SCHEMBL8638582 | 0.89 | HRH1 (0.54) | HRH1PKMTACR1TACR2TACR3 | |
| SCHEMBL8347210 | 0.88 | TACR2 (0.62) | HRH1TACR1TACR2TACR3 | |
| SCHEMBL8640617 | 0.88 | TACR2 (0.50) | HRH1TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |