Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736517 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HTTFFAR1F2RL1NPC1 | |
| SCHEMBL3732071 | 0.86 | RAB9A (0.55) | ALDH1A1HTTFFAR1NPC1POLB | |
| SCHEMBL10551219 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HTTFFAR1NPC1POLB | |
| SCHEMBL3731737 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HTTFFAR1NPC1POLB | |
| SCHEMBL19872027 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HTTFFAR1NPC1POLB | |
| SCHEMBL3758807 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTTFFAR1F2RL1NPC1 | |
| SCHEMBL292834 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTTFFAR1F2RL1NPC1 | |
| SCHEMBL7175493 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HTTFFAR1NPC1POLB | |
| SCHEMBL292835 | 0.79 | NPC1 (0.59) | ALDH1A1HTTFFAR1F2RL1NPC1 | |
| SCHEMBL1871228 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HTTFFAR1F2RL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |