Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637305 | 0.80 | USP2 (0.38) | USP2CCNA2CDK2ADORA1POLB | |
| Ethylene SCHEMBL8990403 | 0.74 | USP2 (0.61) | USP2ADORA1POLBMEN1KMT2A | |
| SCHEMBL1594953 | 0.72 | CDK5 (0.58) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL929846 | 0.71 | CDK5 (0.57) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL8635263 | 0.69 | ADORA1 (0.38) | CDK5CDK5R1CCNA2CDK2ADORA1 | |
| SCHEMBL16840460 | 0.69 | CDK5 (0.55) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL8633321 | 0.68 | MAPT (0.31) | ADORA1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29243610 | 0.67 | CDK5 (0.54) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL18211803 | 0.66 | CDK5 (0.53) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL22869163 | 0.65 | L3MBTL1 (0.45) | ADORA1POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |