Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 9/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.55 |
| ▸ | CDK2 | P24941 | 6/20 | 0.55 |
| ▸ | GRM5 | P41594 | 2/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929846 | 0.98 | CDK5 (0.57) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL16840460 | 0.77 | CDK5 (0.55) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| Hydrochloric Acid SCHEMBL29243610 | 0.76 | CDK5 (0.54) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL18211803 | 0.74 | CDK5 (0.53) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL9959836 | 0.74 | CDK5 (1.00) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL601423 | 0.74 | NOS3 (0.47) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL4115818 | 0.72 | NOS3 (0.45) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL929921 | 0.72 | NOS3 (0.45) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| Ethylene SCHEMBL8636375 | 0.72 | USP2 (0.48) | CDK5CDK5R1CCNA2CDK2GRM5 | |
| SCHEMBL9959918 | 0.72 | CDK5 (0.74) | CDK5CDK5R1CCNA2CDK2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919528-B2 | Antibiotic; bactericides | GLAXOSMITHKLINE LLC (US) | 2011-04-05 | — | — | US | disclosed |
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20050222412-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2005-10-06 | — | — | US | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222412-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | CDK5 2144/4885CDK5R1 2306/4885CCNA2 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.